2024
Budka, Justyna, Dawid Debowski, Shaoshan Mai, Magdalena Narajczyk,
Stanislaw Hac, Krzysztof Rolka, Eirinaios I. Vrettos, Andreas G. Tzakos, and
Iwona Inkielewicz-Stepniak. 2024. Design, Synthesis, and Antitumor Evaluation
of an Opioid Growth Factor Bioconjugate Targeting Pancreatic Ductal
Adenocarcinoma. Pharmaceutics 16 (2): 283.
https://doi.org/10.3390/pharmaceutics16020283.
2023
Tsiailanis, A.D., C.C. Tellis, P. Papakyriakopoulou, A.D. Kostagianni, V.
Gkalpinos, C.M. Chatzigiannis, N. Kostomitsopoulos, G. Valsami, A.D. Tselepis,
and A.G. Tzakos. 2023. "Development of a Novel Apigenin Dosage Form as a
Substitute for the Modern Triple Antithrombotic Regimen". Molecules 28
(5).
https://doi.org/10.3390/molecules28052311.
Diamantis, D., Tsiailanis, A. D., Papaemmanouil, C., Nika, M. C., Kanaki, Z., Golic Grdadolnik, S., … Tzakos, A. G. (2023). "Development of a novel apigenin prodrug programmed for alkaline-phosphatase instructed self-inhibition to combat cancer". Journal of Biomolecular Structure and Dynamics, 1–22.
https://doi.org/10.1080/07391102.2023.2247083.
2022
Alexandri, E., A. Primikyri, G. Papamokos, T. Venianakis, V.K. Gkalpinos, A.G. Tzakos, A. Karydis-Messinis, D. Moschovas, A. Avgeropoulos, and I.P. Gerothanassis. 2022. “NMR and Computational Studies Reveal Novel Aspects in Molecular Recognition of Unsaturated Fatty Acids with Non-Labelled Serum Albumin.” FEBS Journal 289 (18): 5617–36..
https://doi.org/10.1111/febs.16453.
Hajji, N., J. Garcia-Revilla, M.S. Soto, R. Perryman, J. Symington, C.C. Quarles, D.R. Healey, et al. 2022. “Arginine Deprivation Alters Microglial Polarity and Synergizes with Radiation to Eradicate Non-Arginine-Auxotrophic Glioblastoma Tumors.” Journal of Clinical Investigation 132 (6).
https://doi.org/10.1172/JCI142137.
Hernychova, L., E. Alexandri, A.G. Tzakos, M. Zatloukalová, A. Primikyri, I.P. Gerothanassis, L. Uhrik, et al. 2022. “Serum Albumin as a Primary Non-Covalent Binding Protein for Nitro-Oleic Acid.” International Journal of Biological Macromolecules 203:116–29.
https://doi.org/10.1016/j.ijbiomac.2022.01.050.
Koprivica, I., N. Jonić, D. Diamantis, D. Gajić, T. Saksida, N. Pejnović, A.G. Tzakos, and I. Stojanović. 2022. “Phenethyl Ester of Rosmarinic Acid Attenuates Autoimmune Responses during Type 1 Diabetes Development in Mice.” Life Sciences 288.
https://doi.org/10.1016/j.lfs.2021.120184.
Kyrkou, S.G., E.I. Vrettos, D. Gorpas, T. Crook, N. Syed, and A.G.
Tzakos. 2022. Design Principles Governing the Development of Theranostic
Anticancer Agents and Their Nanoformulations with Photoacoustic Properties. Pharmaceutics
14 (2).
https://doi.org/10.3390/pharmaceutics14020362.
Papaemmanouil, C.D., J. Peña-García, A.J. Banegas-Luna,
A.D. Kostagianni, I.P. Gerothanassis, H. Pérez-Sánchez, and A.G.
Tzakos. 2022. ANTIAGE-DB: A Database and Server for the Prediction of
Anti-Aging Compounds Targeting Elastase, Hyaluronidase, and Tyrosinase. Antioxidants
11 (11).
https://doi.org/10.3390/antiox11112268.
Perryman, R., A. Renziehausen, H. Shaye, A.D. Kostagianni, A.D. Tsiailanis, T. Thorne, M.V. Chatziathanasiadou, et al. 2022. “Inhibition of the Angiotensin II Type 2 Receptor AT2R Is a Novel Therapeutic Strategy for Glioblastoma.” Proceedings of the National Academy of Sciences of the United States of America 119 (32).
https://doi.org/10.1073/pnas.2116289119.
Stegnjaić, G., A.D. Tsiailanis, M. Lazarević, V.K. Gkalpinos,
N. Djedovic, T. Antoniou, S. Stanisavljević, et al. 2022. Phenethyl Ester
of Gallic Acid Ameliorates Experimental Autoimmune Encephalomyelitis. Molecules
27 (24).
https://doi.org/10.3390/molecules27248770.
Vakali, V., M. Papadourakis, N. Georgiou, N. Zoupanou, D.A. Diamantis, U.
Javornik, P. Papakyriakopoulou, et al. 2022. Comparative Interaction Studies
of Quercetin with 2-Hydroxyl-Propyl-β-Cyclodextrin and
2,6-Methylated-β-Cyclodextrin. Molecules 27 (17).
https://doi.org/10.3390/molecules27175490.
2021
Diamantis, Dimitrios A., Adamantia Agalou, Maria V. Chatziathanasiadou, Georgios S. Markopoulos, Sofia Bellou, Zoi Kanaki, Timothy Crook, et al. 2021. “Biotin-Yellow a Biotin Guided NIR Turn-on Fluorescent Probe for Cancer Targeted Diagnosis.” Sensors and Actuators B: Chemical 337 (June):129807.
https://doi.org/10.1016/j.snb.2021.129807.
Georgiou, N., V.K. Gkalpinos, S.D. Katsakos, S. Vassiliou, A.G. Tzakos,
and T. Mavromoustakos. 2021. Rational Design and Synthesis of At1r
Antagonists. Molecules 26 (10).
https://doi.org/10.3390/molecules26102927.
Tsiailanis, A.D., A. Renziehausen, S. Karakurt, T. Crook, N. Syed, and
A.G. Tzakos. 2021. Encapsulation of Small Drugs in a Supramolecule Enhances
Solubility, Stability, and Therapeutic Efficacy Against Glioblastoma Multiforme.
Methods in Molecular Biology. Vol. 2207.
https://doi.org/10.1007/978-1-0716-0920-0_14.
Vrettos, E.I., T. Karampelas, N. Sayyad, A. Kougioumtzi, N. Syed, T.
Crook, C. Murphy, C. Tamvakopoulos, and A.G. Tzakos. 2021. Development of
Programmable Gemcitabine-GnRH pro-Drugs Bearing Linker Controllable Click
Oxime Bond Tethers and Preclinical Evaluation against Prostate Cancer. European
Journal of Medicinal Chemistry 211.
https://doi.org/10.1016/j.ejmech.2020.113018.
Vrettos, E.I., and A.G. Tzakos. 2021. Construction of Peptide-Drug
Conjugates for Selective Targeting of Malignant Tumor Cells. Methods in
Molecular Biology. Vol. 2207.
https://doi.org/10.1007/978-1-0716-0920-0_23.
2020
Chatzikonstantinou, A.V., A.D. Tsiailanis, I.P. Gerothanassis, H.
Stamatis, E. Ravera, M. Fragai, C. Luchinat, G. Parigi, and A.G. Tzakos. 2020. The
NMR Tube Bioreactor. Methods in Enzymology. Vol. 633.
https://doi.org/10.1016/bs.mie.2019.10.032.
Diamantis, D.A., M. Oblukova, M.V. Chatziathanasiadou, A. Gemenetzi, C.
Papaemmanouil, P.S. Gerogianni, N. Syed, et al. 2020. Bioinspired Tailoring of
Fluorogenic Thiol Responsive Antioxidant Precursors to Protect Cells against H2O2-Induced
DNA Damage. Free Radical Biology and Medicine 160:540 51.
https://doi.org/10.1016/j.freeradbiomed.2020.08.025.
Tomou, E.-M., M.V. Chatziathanasiadou, P. Chatzopoulou, A.G. Tzakos, and
H. Skaltsa. 2020. NMR-Based Chemical Profiling, Isolation and Evaluation of
the Cytotoxic Potential of the Diterpenoid Siderol from Cultivated Sideritis
Euboea Heldr. Molecules 25 (10).
https://doi.org/10.3390/molecules25102382.
Tsiailanis, A.D., A. Renziehausen, S. Kiriakidi, E.I. Vrettos, G.S.
Markopoulos, N. Sayyad, B. Hirmiz, et al. 2020. Enhancement of Glioblastoma
Multiforme Therapy through a Novel Quercetin-Losartan Hybrid. Free Radical
Biology and Medicine 160:391 402.
https://doi.org/10.1016/j.freeradbiomed.2020.08.007.
Vrettos, E.I., I.E. Valverde, A. Mascarin, P.N. Pallier, L. Cerofolini,
M. Fragai, G. Parigi, et al. 2020. Single Peptide Backbone Surrogate Mutations
to Regulate Angiotensin GPCR Subtype Selectivity. Chemistry - A European
Journal 26 (47): 10690 94.
https://doi.org/10.1002/chem.202000924.
36th European Peptide Symposium and 12th International Peptide Symposium (Sitges, Barcelona, Spain, 08/2022), “Inhibition of the Angiotensin II Type 2 Receptor AT2R is a Novel Therapeutic Strategy for Glioblastoma”, Richard Perryman, Alexander Renziehausen, Hamidreza Shaye, Androniki D. Kostagianni, Antonis D. Tsiailanis, Tom Thorne, Maria V. Chatziathanasiadou, Gregory B. Sivolapenko, Mohamed Ahmed El Mubarak, Gye Won Han, Barbara Zarzycka, Vsevolod Katritch, Guillaume Lebon, Cristiana Lo Nigro, Laura Lattanzio, Sophie Morse, James Choi, Kevin O’Neill, Zoe Kanaki, Apostolos Klinakis, Tim Crook, Vadim Cherezov, Andreas G. Tzakos, and Nelofer Syed.
International Conference on Drug Conjugates for Directed Therapy (Germany, 23–25/08/2023), “Tackling the tumor microenvironment with bioconjugates and near infrared probes”, Andreas Tzakos.
CNRS Laboratoire d'Ingénierie des Systèmes Macromoléculaires (Marseille, France, 04-11/12/2023),“Targeting the tumor microenvironment” - Invited Speaker, Oral Presentation, Andreas Tzakos
1st International Symposium on Advanced Drug Discovery (Ioannina, Greece, 19-20/04/2024), “Novel Theragnostic Photosensitizers for pH-Responsive Therapy and Lipid Droplet Targeted Cancer Treatment” - Oral Presentation, Stavroula Kyrkou
