DEVELOPMENT OF PROGRAMMABLE GEMCITABINE-GNRH PRO-DRUGS BEARING LINKER CONTROLLABLE "CLICK" OXIME BOND TETHERS AND PRECLINICAL EVALUATION AGAINST PROSTATE CANCER.
Vrettos EI, Karampelas T, Sayyad N, Kougioumtzi A, Syed N, Crook T, Murphy C, Tamvakopoulos C, Tzakos AG. Eur J Med Chem. 2020 Nov 12:113018.
doi: 10.1016/j.ejmech.2020.113018. Online ahead of print. PMID: 33223264
CONSTRUCTION OF PEPTIDE-DRUG CONJUGATES FOR SELECTIVE TARGETING OF MALIGNANT TUMOR CELLS
Vrettos EI, Tzakos AG. Methods Mol Biol. 2021;2207:327-338.
doi: 10.1007/978-1-0716-0920-0_23. PMID: 33113145
ENCAPSULATION OF SMALL DRUGS IN A SUPRAMOLECULE ENHANCES SOLUBILITY, STABILITY, AND THERAPEUTIC EFFICACY AGAINST GLIOBLASTOMA MULTIFORME
Tsiailanis AD, Renziehausen A, Karakurt S, Crook T, Syed N, Tzakos AG. Methods Mol Biol. 2021;2207:175-186.
doi: 10.1007/978-1-0716-0920-0_14. PMID: 33113136
BIOINSPIRED TAILORING OF FLUOROGENIC THIOL RESPONSIVE ANTIOXIDANT PRECURSORS TO PROTECT CELLS AGAINST H2O2-INDUCED DNA DAMAGE
Diamantis DA, Oblukova M, Chatziathanasiadou MV, Gemenetzi A, Papaemmanouil C, Gerogianni PS, Syed N, Crook T, Galaris D, Deligiannakis Y, Sokolova R, Tzakos AG. Free Radic Biol Med. 2020 Nov 20;160:540-551.
doi: 10.1016/j.freeradbiomed.2020.08.025. Epub 2020 Aug 29. PMID: 32871232
ENHANCEMENT OF GLIOBLASTOMA MULTIFORME THERAPY THROUGH A NOVEL QUERCETIN-LOSARTAN HYBRID
Tsiailanis AD, Renziehausen A, Kiriakidi S, Vrettos EI, Markopoulos GS, Sayyad N, Hirmiz B, Aguilar MI, Del Borgo MP, Kolettas E, Widdop RE, Mavromoustakos T, Crook T, Syed N, Tzakos AG. Free Radic Biol Med. 2020 Nov 20;160:391-402.
doi: 10.1016/j.freeradbiomed.2020.08.007. Epub 2020 Aug 18. PMID: 32822744
SINGLE PEPTIDE BACKBONE SURROGATE MUTATIONS TO REGULATE ANGIOTENSIN GPCR SUBTYPE SELECTIVITY
Vrettos EI, Valverde IE, Mascarin A, Pallier PN, Cerofolini L, Fragai M, Parigi G, Hirmiz B, Bekas N, Grob NM, Stylos EΚ, Shaye H, Del Borgo M, Aguilar MI, Magnani F, Syed N, Crook T, Waqif E, Ghazaly E, Cherezov V, Widdop RE, Luchinat C, Michael-Titus AT, Mindt TL, Tzakos AG. Chemistry. 2020 Aug 21;26(47):10690-10694.
doi: 10.1002/chem.202000924. Epub 2020 Jul 21. PMID: 32691857
NMR-BASED CHEMICAL PROFILING, ISOLATION AND EVALUATION OF THE CYTOTOXIC POTENTIAL OF THE DITERPENOID SIDEROL FROM CULTIVATED SIDERITIS EUBOEA HELDR.
Tomou EM, Chatziathanasiadou MV, Chatzopoulou P, Tzakos AG, Skaltsa H. Molecules. 2020 May 20;25(10):2382.
doi: 10.3390/molecules25102382. PMID: 32443927
CHAPTER FIVE - THE NMR TUBE BIOREACTOR
Chatzikonstantinou AV, Tsiailanis AD, Gerothanassis IP, Stamatis H, Ravera E, Fragai M, Luchinat C, Parigi G, Tzakos AG. Methods Enzymol. 2020;633:71-101.
doi: 10.1016/bs.mie.2019.10.032. Epub 2019 Dec 26. PMID: 32046854
